{"iri":"http://lmss.sali.org/R6e0IIeTTMVoQl5cw3E3co","id":"R6e0IIeTTMVoQl5cw3E3co","label":"Mantle Cell Lymphoma","definition":"Mantle cell lymphoma is an aggressive type of non-Hodgkin lymphoma that originates in the B-cells located in the mantle zone of the lymph nodes. It is characterized by a specific genetic mutation involving the overexpression of the cyclin D1 protein, leading to uncontrolled cell growth.","prefLabels":[],"altLabels":["Aggressive B-Cell Lymphoma","Cyclin D1 Positive Lymphoma","Mantle Zone Lymphoma"],"examples":[],"notes":[],"sources":["https://www.ssa.gov/disability/professionals/bluebook/13.00-NeoplasticDiseases-Malignant-Adult.htm#13_05"],"branch":{"iri":"http://lmss.sali.org/R7L5eLIzH0CpOUE74uJvSjL","label":"Legal Entity"},"parents":[{"iri":"http://lmss.sali.org/RBFOZ6k0p0FnZyMzuijRYdU","id":"RBFOZ6k0p0FnZyMzuijRYdU","label":"Non-Hodgkin Lymphoma"}],"children":[],"relations":[],"url":"https://lmss.io/tag/R6e0IIeTTMVoQl5cw3E3co/","source":{"repo":"sali-legal/LMSS","ref":"3f9ac0c9357b2a971582ae79ede243511d47811d","channel":"pre-release"}}