Systemic Sclerosis
Systemic sclerosis (also known as scleroderma) constitutes a spectrum of disease in which thickening of the skin is the clinical hallmark. Raynaud's phenomenon, often medically severe and progressive, is present frequently and may be the peripheral manifestation of a vasospastic abnormality in the heart, lungs, and kidneys. The CREST syndrome (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) is a variant that may slowly progress over years to the generalized process, systemic sclerosis.
Also known as
Scleroderma, Autoimmune Connective Tissue Disorder, Progressive Systemic Sclerosis
Ancestry path
Generated from sali-legal/LMSS at 3f9ac0c9357b (2026-03-10). JSON